Researchers in the field of connectomics endeavor to analyze the complex synaptic network formed by the billions of interconnected neurons. By thinly slicing neural tissue and imaging each section with a scanning electron microscope at high resolution, fine structural details can be visualized. Careful delineation of each neuron in the 3-D volume allows for the high-resolution mapping of all connections made by each cell, providing a detailed wiring diagram of the brain: the connectome. The sheer size and complexity of this scientific challenge is daunting. Tens of thousands of sections or more need to collected and hundreds of thousands of images recorded, resulting in many terabytes of data that require rapid processing, making connectomics a real “speed game.” Automated sample preparation robots and high throughput electron microscopes have now become available, bringing the promise of a larger (1 mm³), high-resolution connectome within reach. However, extracting neuronal circuit information from such large datasets is still a daunting task. This webinar will outline the challenges of connectomics, explain the latest methodological developments that are bringing imaging and data analysis closer to the desired throughput, and provide insights into how this research can provide a deeper understanding of brain function and dysfunction.

During the webinar, the speakers will:
•    Provide an overview of high-resolution connectomics and the methods currently used to create dense reconstructions of the brain
•    Discuss new advances in the field that are enabling researchers to take the next quantum leap
•    Present their own research and provide some thoughts on how connectomics might evolve in the future
•    Discuss the limitations of what can be learned with these new approaches
•    Answer your questions live during the webinar!

Register

Date: Monday, November 3, 2014
Time: 12 Noon Eastern, 9 a.m. Pacific, 5 p.m. UK, 6 p.m. Central Europe
Duration: 1 hour

Views: 66

Replies to This Discussion

Hi,,no i cannot chat about this much,but why i posted is i thought  this is a bit too scientific for me,its my brothers world hed answer this (hes the brains of the family and like me in music his things been physics) so i thought id phone him see what he said,,i said "thought id see what youd say about this as its above me really and no-one has answerd it,,,,i only read half of it when he explained it back saying its obiously like a pc,then he said "my 10 year old gets it" i was in the car he said,talking to someone id given a lift too,we got on this subject and my brother said--the brain is not the pc its the keyboard as the keyboard is the connection to thinking and the brain doesant think its the conection to that,,,then he said    and little tommy only age10 at the time in the backseat said"and the mouse is the heart as its connection is the most analog"

That sounds so deep to me,,he build my last computer when he was 8 i had no problems with it and ive only resently had a new one that was 7 years ago :-)  my brothers other son is 28  hes been self employed on the internet since he was 14,,My brother started on computers age 11 in 1974,,his sons from age 3

Hi - yes, the Science Group is for really technically peer-reviewed (etc.) posts. However - some stuff people can get a gist of, and skim some good info. In that sense it is for all.

Your brother (and family) sounds interesting! pass the info on!

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